Substantial gaps exist in our knowledge of exposure and in our understanding of the metabolism, dose, and toxicity of diverse arsenic compounds in foods. The goal of this Pilot Project was to determine the acute alterations in metabolism and toxicity of arsenicals ingested in foods in humans and mice. In the current mouse study, arsenic metabolism and biomarker expression was investigated and the elements of organ-specific metabolism were evaluated.
Margaret Kurzius-Spencer received her M.P.H. (1997) and Ph.D. (2012) in Epidemiology from the University of Arizona, Mel & Enid Zuckerman College of Public Health, and is currently an Assistant Professor, in the Department of Pediatrics and College of Public Health. Prior to receiving her doctorate, Dr.